Bupropion (brand names: Wellbutrin, Zyban, Wellbutrin SR)

Posted on March 17th, 2008 in Medicines by Work

An antidepressant medication that affects chemicals within the brain that nerves use to send messages to each other. These chemical messengers are called neurotransmitters. The neurotransmitters that are released by nerves are taken up again by the nerves that release them for reuse (referred to as reuptake). Many experts believe that depression is caused by an imbalance among the amounts of neurotransmitters that are released. Bupropion is unrelated to other antidepressants. It works by inhibiting the reuptake of the neurotransmitters dopamine, serotonin, and norepinephrine, resulting in more of these chemicals being available to transmit messages to other nerves. Bupropion is unique in that its major effect is on dopamine. Wellbutrin and Wellbutrin SR are used for the management of depression. Zyban has been approved as an aid to patients who want to quit smoking. Generic is not available.

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